Single-cell Sequencing and Methylation: Methods and...

Single-cell Sequencing and Methylation: Methods and Clinical Applications

Buwei Yu, Jiaqiang Zhang, Yiming Zeng, Li Li, Xiangdong Wang
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With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.

Categorias:
Ano:
2020
Edição:
1st ed.
Editora:
Springer Singapore;Springer
Idioma:
english
ISBN 10:
9811544948
ISBN 13:
9789811544941
Série:
Advances in Experimental Medicine and Biology 1255
Arquivo:
PDF, 8.83 MB
IPFS:
CID , CID Blake2b
english, 2020
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